Chitosan/hyaluronic acid polyelectrolyte complex hydrogels in the management of burn wounds

Rev Med Chir Soc Med Nat Iasi. 2013 Apr-Jun;117(2):565-71.

Abstract

Aim: This paper is a short review on the state-of-the-art of the use of polyelectrolyte complexes containing polysaccharides for wound and burn healing and treatment using the chitosan/hyaluronic acid polyelectrolyte complex (PEC) hydrogel.

Results and conclusions: PEC is suitable for wound healing because a wet treatment can be realized and both components of PEC contribute by their properties to the enhanced antimicrobial activity, promote wound healing and prevent wound damage during treatment.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bandages
  • Biocompatible Materials / chemical synthesis
  • Biocompatible Materials / chemistry
  • Biocompatible Materials / pharmacology*
  • Burns / drug therapy*
  • Burns / therapy
  • Chitosan / chemical synthesis
  • Chitosan / chemistry
  • Chitosan / pharmacology*
  • Drug Therapy, Combination / methods
  • Electrolytes
  • Humans
  • Hyaluronic Acid / chemical synthesis
  • Hyaluronic Acid / chemistry
  • Hyaluronic Acid / pharmacology*
  • Hydrogels / chemistry
  • Treatment Outcome
  • Viscosupplements / chemical synthesis
  • Viscosupplements / chemistry
  • Viscosupplements / pharmacology*

Substances

  • Biocompatible Materials
  • Electrolytes
  • Hydrogels
  • Viscosupplements
  • Hyaluronic Acid
  • Chitosan