Influence of metabolic syndrome profile on cardiovascular risk

Rev Med Chir Soc Med Nat Iasi. 2013 Apr-Jun;117(2):308-14.

Abstract

Aim: The trial was conducted on patients with metabolic syndrome hospitalized between 01.01.2012-31.12.2012 at Cardiovascular Rehabilitation Clinic of the Rehabilitation Hospital Iasi.

Material and methods: Patients included in the study were analyzed according to age and sex, criteria for the clinical definition of the metabolic syndrome, known cardiovascular diseases, diabetes mellitus type 2 or type 1.

Results: Metabolic syndrome components analysis showed statistical differences between the sexes, in case of certain cardiovascular risk factors. The frequency of cardiovascular risk factors (obesity, hypertriglyceridemia, hypertension, glycemic profile modification) was higher among women, the only risk factor most common in males was the decrease of HDL cholesterol. The statistically significant difference occurs in hypertriglyceridemia (p = 0.001) and HDL-Cholesterol (p = 0.000). Patients included in the study were studied depending on the frequency of the main cardiovascular diseases, secondary to the metabolic syndrome: ischemic heart disease, stroke, peripheral arterial disease of the lower extremities.

Conclusions: Association of impaired glucose tolerance/diabetes mellitus, arterial hypertension and hypertriglyceridemia recorded an additional risk of developing CIC or ischemic stroke, independent of sex.

MeSH terms

  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Body Mass Index
  • Cardiovascular Diseases / blood
  • Cardiovascular Diseases / diagnosis
  • Cardiovascular Diseases / etiology*
  • Cholesterol, HDL / blood
  • Diabetes Mellitus, Type 2 / complications
  • Female
  • Humans
  • Hypertension / complications
  • Male
  • Metabolic Syndrome / blood
  • Metabolic Syndrome / complications*
  • Metabolic Syndrome / diagnosis
  • Middle Aged
  • Obesity, Abdominal / complications
  • Rehabilitation Centers
  • Risk Assessment
  • Risk Factors
  • Sex Distribution
  • Triglycerides / blood

Substances

  • Biomarkers
  • Cholesterol, HDL
  • Triglycerides