Pancreaticogastrostomy following distal pancreatectomy prevents pancreatic fistula-related complications

J Hepatobiliary Pancreat Sci. 2014 Jul;21(7):473-8. doi: 10.1002/jhbp.59. Epub 2013 Dec 15.

Abstract

Background: The most common postoperative complication after distal pancreatectomy (DP) is still postoperative pancreatic fistula (POPF), which is closely associated with other major complications and remains an unsolved problem.

Methods: This retrospective study included 47 consecutive patients who underwent a distal pancreatectomy with (DP-PG group, n = 21) or without (DP group, n = 26) duct-to-mucosa pancreaticogastrostomy from June 2010 to May 2012. Clinical data including POPF-related complications (POPF, fluid collection, intra-abdominal abscess, bleeding and delayed gastric emptying) as a primary endpoint were compared between the two groups.

Results: The frequencies of POPF-related complications as well as overall POPF and complications in the DP-PG group were lower than in the DP group (P = 0.037, P < 0.001, respectively). The 30 days morbidity after hospital discharge in the DP-PG group was less than in the DP group (P = 0.014). In both groups median hospital stay was similar. Although additional time needed for pancreaticogastrostomy was 35 (20-55) min, there was no difference in operative times. Patients in the DP group had a higher medical cost for hospitalization than the DP-PG group (P = 0.048).

Conclusion: Pancreaticogastrostomy as an additional procedure following distal pancreatectomy was associated with a reduced rate of POPF-related complications that resulted in relatively lower medical cost for hospitalization.

Keywords: Distal pancreatectomy; Medical cost; Pancreatic fistula-related complication; Pancreaticogastrostomy.

MeSH terms

  • Adult
  • Aged
  • Anastomosis, Surgical
  • Digestive System Surgical Procedures / methods
  • Female
  • Gastrostomy / methods*
  • Humans
  • Male
  • Middle Aged
  • Pancreas / surgery*
  • Pancreatectomy / adverse effects*
  • Pancreatic Fistula / complications*
  • Pancreatic Neoplasms / surgery
  • Postoperative Complications / prevention & control
  • Retrospective Studies