Abstract
We report a small-molecule two-photon fluorescent probe (ANa2) for Na(+) that shows a strong TPEF enhancement in response to Na(+) and can be easily loaded into live cells and can real time monitor the fluctuation of [Na]i in live cells and living tissue at more than 100 μm depth.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Astrocytes
-
Fluorescent Dyes / pharmacology*
-
Glutamic Acid / pharmacology
-
HeLa Cells
-
Heterocyclic Compounds, 1-Ring / pharmacology*
-
Hippocampus / metabolism
-
Histamine / pharmacology
-
Humans
-
In Vitro Techniques
-
Microscopy, Fluorescence, Multiphoton
-
Proline / analogs & derivatives*
-
Proline / pharmacology
-
Rats
-
Sodium / metabolism*
Substances
-
Fluorescent Dyes
-
Heterocyclic Compounds, 1-Ring
-
Glutamic Acid
-
Histamine
-
Proline
-
Sodium