Trends in the use of psychotropic drugs in people with intellectual disability in Taiwan: a nationwide outpatient service study, 1997-2007

Res Dev Disabil. 2014 Feb;35(2):364-72. doi: 10.1016/j.ridd.2013.11.011. Epub 2013 Dec 13.

Abstract

This study aims to examine trends in outpatient psychotropic drug use among people with intellectual disabilities in Taiwan. The NHI outpatient medication records between January 1, 1997 and December 31, 2007 for people with intellectual disabilities were analyzed to observe the percent change, prevalence and prescription trends in psychotropic drugs. The overall prevalence of psychotropic medication increased from 17.82% to 23.22% during the study period. Results from stepwise logistic analysis demonstrated that females, the elderly, and individuals suffering from catastrophic disease were more prone to receive psychotropic drugs and that those with mild intellectual disability were less likely to receive psychotropic drugs. The percentage change in prescription rates of antipsychotics, hypnotics/sedatives, and antidepressants were 85.30%, 127.25%, and 167.50%, respectively, and the trends were statistically significant (p<0.05). Taiwan's NHI program and off-label use of psychotropic drugs might have attributed to this trend.

Keywords: Intellectual disability; Psychotropic drugs.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antidepressive Agents / therapeutic use*
  • Antipsychotic Agents / therapeutic use*
  • Child
  • Child, Preschool
  • Databases, Factual
  • Female
  • Humans
  • Hypnotics and Sedatives / therapeutic use*
  • Intellectual Disability* / complications
  • Male
  • Mental Disorders / complications
  • Mental Disorders / drug therapy*
  • Middle Aged
  • Off-Label Use / statistics & numerical data
  • Outpatients
  • Practice Patterns, Physicians' / trends*
  • Psychotropic Drugs / therapeutic use
  • Retrospective Studies
  • Taiwan
  • Young Adult

Substances

  • Antidepressive Agents
  • Antipsychotic Agents
  • Hypnotics and Sedatives
  • Psychotropic Drugs