Frequency of dengue virus infection in blood donors in Sistan and Baluchestan province in Iran

Transfus Apher Sci. 2014 Feb;50(1):59-62. doi: 10.1016/j.transci.2013.07.034. Epub 2013 Nov 28.

Abstract

Risk of dengue virus in the blood supply has been demonstrated in recent studies. In this paper, Chabahar in Sistan and Baluchestan province, south east of Iran, was selected for studying dengue infection because of its climatic and geographical situation in the middle of the transit way between East Asia and other countries. The blood samples were taken from volunteer healthy donors who were referred to the Chabahar Blood Center for blood donation. The presence of dengue virus (DENV) was studied by detecting IgG to DENV by enzyme linked immune sorbent assay (ELISA). Reactive ELISA results were confirmed by an immune flouorescence assay (IFA). According to the results, some of the healthy donors were infected by DENV, which could not been recognized in donor selection. Therefore, special attention should be paid to the criteria of donor selection and additional screening tests are recommended.

Keywords: Blood donor; Dengue virus; Iran.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Donors*
  • Dengue / blood
  • Dengue / epidemiology*
  • Dengue / virology*
  • Dengue Virus
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Fluorescent Antibody Technique
  • Geography
  • Healthy Volunteers
  • Humans
  • Immunoglobulin G / blood
  • Iran / epidemiology
  • Male

Substances

  • Immunoglobulin G