Abstract
A novel and highly practical reaction for the copper-catalyzed intermolecular cyanotrifluoromethylation of alkenes is presented here. This methodology provides a general and straightforward way to synthesize a variety of useful CF3-containing nitriles, which can be used for further preparation of pharmaceutically and agrochemically important compounds in synthetic organic chemistry.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemistry*
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Catalysis
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Copper / chemistry*
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Hydrocarbons, Fluorinated / chemical synthesis*
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Hydrocarbons, Fluorinated / chemistry
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Methylation
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Molecular Structure
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Nitriles / chemical synthesis*
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Nitriles / chemistry
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Organometallic Compounds / chemistry*
Substances
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Alkenes
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Hydrocarbons, Fluorinated
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Nitriles
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Organometallic Compounds
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Copper