BCL6 corepressor gene dysregulation due to chromosomal translocation in acute myeloid leukemia: a new mechanism based on long non-coding RNA dislocation?

Leuk Lymphoma. 2014 Sep;55(9):2199-201. doi: 10.3109/10428194.2013.874009. Epub 2014 Feb 24.

Authors

Antonella Zagaria¹, Luisa Anelli, Paola Casieri, Nicoletta Coccaro, Giuseppina Tota, Crescenzio Francesco Minervini, Angela Minervini, Luciana Impera, Claudia Brunetti, Paola Orsini, Angelo Cellamare, Giorgina Specchia, Francesco Albano

Affiliation

¹ Hematology Section, Department of Emergency and Organ Transplantation (D.E.T.O.), University of Bari , Bari , Italy.

PMID: 24325634
DOI: 10.3109/10428194.2013.874009

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Abnormal Karyotype
Aged, 80 and over
Gene Expression Regulation, Leukemic*
Humans
Immunophenotyping
In Situ Hybridization, Fluorescence
Leukemia, Myeloid, Acute / diagnosis
Leukemia, Myeloid, Acute / genetics*
Male
Proto-Oncogene Proteins / genetics*
RNA, Long Noncoding / genetics*
Repressor Proteins / genetics*
Translocation, Genetic*

Substances

BCOR protein, human
Proto-Oncogene Proteins
RNA, Long Noncoding
Repressor Proteins