Increase in lactate yield by growing Corynebacterium glutamicum in a bioelectrochemical reactor

Kengo Sasaki; Yota Tsuge; Daisuke Sasaki; Akihiko Kondo

doi:10.1016/j.jbiosc.2013.10.026

Increase in lactate yield by growing Corynebacterium glutamicum in a bioelectrochemical reactor

J Biosci Bioeng. 2014 May;117(5):598-601. doi: 10.1016/j.jbiosc.2013.10.026. Epub 2013 Dec 4.

Authors

Kengo Sasaki¹, Yota Tsuge¹, Daisuke Sasaki², Akihiko Kondo³

Affiliations

¹ Organization of Advanced Science and Technology, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan.
² Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan.
³ Department of Chemical Science and Engineering, Graduate School of Engineering, Kobe University, 1-1 Rokkodai-cho, Nada-ku, Kobe, Hyogo 657-8501, Japan; Biomass Engineering Program, RIKEN, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan; Department of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea University, Seoul 136-713, Republic of Korea.

PMID: 24315531
DOI: 10.1016/j.jbiosc.2013.10.026

Abstract

Under conditions conductive to growth, Corynebacterium glutamicum showed higher lactate yield from glucose (1.62 ± 0.04) in a bioelectrochemical reactor including 0.2 mM of anthraquinone 2,6-disulfonate with the electrode potential regulated at -0.6 V (vs. Ag/AgCl) than in a non-regulated environment (1.10 ± 0.03), clarifying that low cathodic potential is beneficial for lactate production.

Keywords: Bioelectrochemical reactor; Corynebacterium glutamicum; Growing conditions; Lactate; Reducing power.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bioreactors*
Corynebacterium glutamicum / chemistry
Corynebacterium glutamicum / growth & development*
Corynebacterium glutamicum / metabolism*
Electrodes
Electrophysiological Phenomena*
Glucose / metabolism
Lactic Acid / biosynthesis*
Oxidation-Reduction

Substances

Lactic Acid
Glucose