[Integrative medicine in the management of functional dyspepsia. Role of the herbal preparation STW5]

Gastroenterol Hepatol. 2014 Apr;37(4):256-61. doi: 10.1016/j.gastrohep.2013.10.001. Epub 2013 Dec 5.
[Article in Spanish]

Abstract

Functional dyspepsia is defined as a group of symptoms, whether related or unrelated to intake, localized in the upper abdomen, that manifest in the form of discomfort or epigastric pain, postprandial fullness and early satiety, in the absence of any demonstrable organic or structural anomaly. The etiopathogenesis and physiopathology of the process are unknown but factors that may be involved include gastric motility disorders, visceral hypersensitivity, psychological and genetic factors, Helicobacter pylori infection, and gastric acid hypersecretion. There is still no etiological treatment and consequently treatment is empirical and based on symptoms. This article reviews the main therapeutic options currently available, with special emphasis on the use of certain phytoceuticals (STW 5), in an attempt to integrate with traditional scientific medicine. This article also proposes an integrative therapeutic algorithm.

Keywords: Antidepressants; Complementary and alternative medicine; Dispepsia; Dyspepsia; Fitoterapia; Helicobacter pylori; Medicina complementaria y alternativa; Phytotherapy; Procinéticos antidepresivos; Prokinetics; STW 5.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Algorithms
  • Anti-Anxiety Agents / therapeutic use
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Antidepressive Agents / therapeutic use
  • Breath Tests
  • Clinical Trials as Topic
  • Combined Modality Therapy
  • Dyspepsia / drug therapy*
  • Dyspepsia / etiology
  • Dyspepsia / psychology
  • Gastric Emptying / drug effects
  • Gastritis / complications
  • Gastritis / drug therapy
  • Gastrointestinal Motility / drug effects
  • Helicobacter Infections / complications
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / drug therapy
  • Humans
  • Integrative Medicine / methods*
  • Meta-Analysis as Topic
  • Multicenter Studies as Topic
  • Phytotherapy*
  • Plant Extracts / therapeutic use*
  • Psychotherapy
  • Sulpiride / analogs & derivatives
  • Sulpiride / therapeutic use

Substances

  • Anti-Anxiety Agents
  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents
  • Antidepressive Agents
  • Plant Extracts
  • iberogast
  • Sulpiride
  • levosulpiride