(9E)-9-benzylidene-2-methylsulfanyl-5-phenyl-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-4(3H)-one: a hydrogen-bonded R2(2)(8) dimer

Diana Becerra; Braulio Insuasty; Justo Cobo; Christopher Glidewell

doi:10.1107/S010827011303059X

(9E)-9-benzylidene-2-methylsulfanyl-5-phenyl-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-4(3H)-one: a hydrogen-bonded R2(2)(8) dimer

Acta Crystallogr C. 2013 Dec 15;69(Pt 12):1524-6. doi: 10.1107/S010827011303059X. Epub 2013 Nov 13.

Authors

Diana Becerra¹, Braulio Insuasty, Justo Cobo, Christopher Glidewell

Affiliation

¹ Departamento de Química, Universidad de Valle, AA 25360 Cali, Colombia.

PMID: 24311504
DOI: 10.1107/S010827011303059X

Abstract

In the molecule of the title compound, C25H21N3OS, which was prepared by mild oxidation of the corresponding 5,6,7,8,9,10-hexahydro analogue, the fused carbocyclic ring adopts an envelope conformation. Pairs of molecules are linked into cyclic centrosymmetric dimers by pairs of inversion-related N-H···O hydrogen bonds.

Keywords: biological activity; crystal structure; hydrogen-bonded dimer; tetrahydropyrimidin-4(3H)-one.