Application of magnetic nanoparticle for controlled tissue assembly and tissue engineering

Arch Pharm Res. 2014 Jan;37(1):120-8. doi: 10.1007/s12272-013-0303-3. Epub 2013 Dec 6.

Abstract

Magnetic nanoparticles have been subjected to extensive studies in the past few decades owing to their promising potentials in biomedical applications. The versatile intrinsic properties of magnetic nanoparticles enable their use in many biomedical applications. Recently, magnetic nanoparticles were utilized to control the cell's function. In addition, intracellular delivery of magnetic nanoparticles allowed cell's positioning by appropriate use of magnetic field and created cellular cluster. Furthermore, magnetic nanoparticles have been utilized to assemble more complex tissue structures than those that are achieved by conventional scaffold-based tissue engineering strategies. This review addresses recent work in the use magnetic nanoparticle for controlled tissue assembly and complex tissue formation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Culture Techniques
  • Cell Differentiation
  • Cell Movement
  • Cells, Cultured
  • Humans
  • Magnetics / methods*
  • Magnetite Nanoparticles*
  • Nanomedicine / methods
  • Organogenesis
  • Phenotype
  • Regenerative Medicine / methods*
  • Tissue Engineering / methods*

Substances

  • Magnetite Nanoparticles