ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells

Gut. 2014 Jul;63(7):1038-9. doi: 10.1136/gutjnl-2013-306103. Epub 2013 Dec 4.

Authors

Arthur Kaser¹, Richard S Blumberg²

Affiliations

¹ Division of Gastroenterology and Hepatology, Department of Medicine, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.
² Division of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

No abstract available

Keywords: IBD.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Autophagy-Related Proteins
Carrier Proteins / genetics*
Crohn Disease / genetics*
Endoplasmic Reticulum Stress / genetics*
Genetic Predisposition to Disease*
Humans
Paneth Cells / metabolism*
Polymorphism, Single Nucleotide*

Substances

ATG16L1 protein, human
Autophagy-Related Proteins
Carrier Proteins

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