Therapeutic status-dependent thymic changes on 18F-FDG PET/CT in an adult patient with lymphoma who underwent 2 phases of chemotherapy

Clin Nucl Med. 2014 Mar;39(3):e243-5. doi: 10.1097/RLU.0000000000000269.

Abstract

A 31-year-old woman who underwent 2 phases of chemotherapy for Hodgkin lymphoma subsequently underwent 8 F-FDG PET/CT scans for staging and treatment response evaluation. The images revealed that the Hounsfield unit and SUV of the thymus changed with the therapeutic status; both decreased to the lowest level 0.5 months after chemotherapy and increased to the highest level 8 to 12 months after the end of treatment. Interestingly, we found a positive correlation between the thymic Hounsfield unit and SUV, with a Spearman correlation coefficient of 0.946 (P < 0.001).

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Lymphoma / diagnostic imaging*
  • Lymphoma / drug therapy*
  • Multimodal Imaging*
  • Positron-Emission Tomography*
  • Thymus Gland
  • Tomography, X-Ray Computed*

Substances

  • Fluorodeoxyglucose F18