Gadolinium-binding cyclic hexapeptoids: synthesis and relaxometric properties

Org Biomol Chem. 2014 Jan 21;12(3):424-31. doi: 10.1039/c3ob42029a. Epub 2013 Nov 29.

Abstract

Two new cyclic hexapeptoids incorporating N-carboxyethylglycine and N-methoxyethylglycine residues are able to efficiently bind Gd(3+). Their thermodynamic stabilities and relaxivities have been assessed by (1)H-relaxometric investigations.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gadolinium / chemistry*
  • Ligands
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds / chemical synthesis*
  • Organometallic Compounds / chemistry*
  • Peptides, Cyclic / chemistry*
  • Thermodynamics

Substances

  • Ligands
  • Organometallic Compounds
  • Peptides, Cyclic
  • Gadolinium