Salivary gland dysfunction and xerostomia in Sjögren's syndrome

Siri Beier Jensen; Arjan Vissink

doi:10.1016/j.coms.2013.09.003

Salivary gland dysfunction and xerostomia in Sjögren's syndrome

Oral Maxillofac Surg Clin North Am. 2014 Feb;26(1):35-53. doi: 10.1016/j.coms.2013.09.003.

Authors

Siri Beier Jensen¹, Arjan Vissink

Affiliation

¹ Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, Nørre Allé 20, 2200 Copenhagen N, Denmark. Electronic address: sirib@sund.ku.dk.

PMID: 24287192
DOI: 10.1016/j.coms.2013.09.003

Abstract

In this article, salivary gland dysfunction and xerostomia in Sjögren's syndrome (SS) are discussed, with a focus on the pathophysiology of salivary dysfunction in SS, the clinical presentation of dry mouth in SS, how to assess salivary gland hypofunction and xerostomia in SS, and the impact of salivary gland dysfunction on quality of life in patients with SS.

Keywords: Hyposalivation; Salivary gland dysfunction; Sialometry; Sjögren's syndrome; Subjective assessment; Xerostomia.

Publication types

Review

MeSH terms

Humans
Saliva / chemistry
Saliva / metabolism
Salivary Glands / physiopathology*
Sjogren's Syndrome / physiopathology*
Xerostomia / physiopathology