Pregnancy and neonatal outcomes of women receiving compounded 17-alpha hydroxyprogesterone at San Juan City hospital

Bol Asoc Med P R. 2013;105(3):25-8.

Abstract

Objective: To describe the pregnancy and neonatal outcomes of women receiving 17alpha-hydroxyprogesterone to prevent subsequent preterm birth in our institution.

Methods: Forty-two patient received treatment by VITA healthcare and their charts were reviewed for results and outcomes.

Results: An increase in average gestational age at the time of delivery was noticed as well as an increase in weeks gained compared to previous preterm birth.

Discussion: More than 75% of the patients prolonged their pregnancy with the use of 17alpha-hydroxyprogesterone. Continuation of the study and stratifying patients will help in identifying other risk factors and establishing criteria for improved prevention of preterm birth and prognosis.

Publication types

  • Observational Study

MeSH terms

  • 17-alpha-Hydroxyprogesterone / administration & dosage
  • 17-alpha-Hydroxyprogesterone / therapeutic use*
  • Adult
  • Birth Weight
  • Drug Evaluation
  • Female
  • Gestational Age
  • Home Care Services, Hospital-Based
  • Humans
  • Infant, Newborn
  • Infant, Premature*
  • Injections, Intramuscular
  • Male
  • Obstetric Labor, Premature / drug therapy*
  • Pregnancy
  • Pregnancy Outcome
  • Premature Birth / prevention & control*
  • Puerto Rico
  • Recurrence
  • Stillbirth / epidemiology
  • Tocolytic Agents / administration & dosage
  • Tocolytic Agents / therapeutic use*
  • Urban Population / statistics & numerical data

Substances

  • Tocolytic Agents
  • 17-alpha-Hydroxyprogesterone