Abstract
Nontoxic CO-releasing dirhodium complexes act as inhibitors of NO in stimulated macrophage cells, suggesting that novel antiinflammatory treatments could involve the use of these types of binuclear complexes.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Anti-Inflammatory Agents / chemistry
-
Anti-Inflammatory Agents / pharmacology*
-
Biological Assay
-
Carbon Monoxide / chemistry
-
Carbon Monoxide / metabolism*
-
Cell Line
-
Coordination Complexes / chemistry
-
Coordination Complexes / pharmacology*
-
Humans
-
Macrophages / drug effects*
-
Macrophages / metabolism
-
Models, Biological
-
Nitric Oxide / antagonists & inhibitors*
-
Rhodium / chemistry
-
Rhodium / pharmacology*
Substances
-
Anti-Inflammatory Agents
-
Coordination Complexes
-
Nitric Oxide
-
Carbon Monoxide
-
Rhodium