Regioselective palladium-catalyzed phosphonation of coumarins with dialkyl H-phosphonates via C-H functionalization

Xia Mi; Mengmeng Huang; Jianye Zhang; Chenyang Wang; Yangjie Wu

doi:10.1021/ol4031167

Regioselective palladium-catalyzed phosphonation of coumarins with dialkyl H-phosphonates via C-H functionalization

Org Lett. 2013 Dec 20;15(24):6266-9. doi: 10.1021/ol4031167. Epub 2013 Nov 25.

Authors

Xia Mi¹, Mengmeng Huang, Jianye Zhang, Chenyang Wang, Yangjie Wu

Affiliation

¹ College of Chemistry and Molecular Engineering, Henan Key Laboratory of Chemical Biology and Organic Chemistry, Key Laboratory of Applied Chemistry of Henan Universities, Zhengzhou University , Zhengzhou 450052, P.R. China.

PMID: 24274120
DOI: 10.1021/ol4031167

Abstract

A novel Pd(II)-catalyzed dehydrogenative cross-coupling reaction between coumarins and H-phosphonates has been developed to give the corresponding 3-phosphonated products in moderate to good yields with high selectivity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Coumarins / chemistry*
Molecular Structure
Organometallic Compounds / chemistry*
Organophosphorus Compounds / chemistry*
Palladium / chemistry*
Stereoisomerism

Substances

Coumarins
Organometallic Compounds
Organophosphorus Compounds
Palladium