Body temperature reduction of graphene oxide through chitosan functionalisation and its application in drug delivery

Richard Justin; Biqiong Chen

doi:10.1016/j.msec.2013.10.010

Body temperature reduction of graphene oxide through chitosan functionalisation and its application in drug delivery

Mater Sci Eng C Mater Biol Appl. 2014 Jan 1:34:50-3. doi: 10.1016/j.msec.2013.10.010. Epub 2013 Oct 22.

Authors

Richard Justin¹, Biqiong Chen

Affiliation

¹ Department of Materials Science and Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD, United Kingdom.

PMID: 24268232
DOI: 10.1016/j.msec.2013.10.010

Abstract

The reduction of graphene oxide at body temperature by using a biopolymer, chitosan, was proven to be successful. This biocompatible reduction approach will provide a versatile platform for applying graphene in biomedical fields including tissue engineering and therapeutic delivery. The use of this approach for therapeutic delivery is demonstrated.

Keywords: Chitosan; Drug delivery; Graphene; Reduction.

MeSH terms

Body Temperature*
Chitosan / chemistry*
Drug Delivery Systems*
Graphite / chemistry*
Oxidation-Reduction
Oxides / chemistry*
Spectroscopy, Fourier Transform Infrared
X-Ray Diffraction

Substances

Oxides
Graphite
Chitosan