Abstract
Molecular rotors have emerged as versatile probes for microscopic viscosity in live cells, however, the exclusive localisation of rotors in the plasma membrane has remained elusive. We report the synthesis, spectroscopic characterisation and live cell imaging of a new BODIPY-based molecular rotor suitable for mapping viscosity in the cell plasma membrane.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemistry*
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Cell Membrane / chemistry*
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Female
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Fluorescent Dyes / chemistry*
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Humans
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Microscopy, Confocal
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Ovarian Neoplasms / pathology*
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Spectrometry, Fluorescence
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Tumor Cells, Cultured
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Viscosity*
Substances
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4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Fluorescent Dyes