Effects of chlorhexidine-containing adhesives on the durability of resin-dentine interfaces

Rodrigo Stanislawczuk; Fabiane Pereira; Miguel Angel Muñoz; Issis Luque; Paulo Vitor Farago; Alessandra Reis; Alessandro D Loguercio

doi:10.1016/j.jdent.2013.11.002

Effects of chlorhexidine-containing adhesives on the durability of resin-dentine interfaces

J Dent. 2014 Jan;42(1):39-47. doi: 10.1016/j.jdent.2013.11.002. Epub 2013 Nov 16.

Authors

Rodrigo Stanislawczuk¹, Fabiane Pereira², Miguel Angel Muñoz¹, Issis Luque¹, Paulo Vitor Farago³, Alessandra Reis², Alessandro D Loguercio⁴

Affiliations

¹ Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil; Department of Restorative, Dentistry, Center of High Education of Campos Gerais, Ponta Grossa, Brazil.
² Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil.
³ Department of Pharmaceutical Sciences, State University of Ponta Grossa, Ponta Grossa, Brazil.
⁴ Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Brazil. Electronic address: aloguercio@hotmail.com.

PMID: 24252801
DOI: 10.1016/j.jdent.2013.11.002

Abstract

Objectives: This study evaluated the effect of addition of diacetate CHX in different concentrations into two simplified etch-and-rinse (ER) adhesive systems (XP Bond [XP] and Ambar {AM}) on the ultimate tensile strength (UTS), degree of conversion (DC), 60-day cumulative water sorption (WS), solubility (SO) and CHX release (CR) as well as the immediate (IM) and 1-year (1Y) resin-dentine bond strength (μTBS) and nanoleakage (NL).

Methods: Ten experimental adhesive systems were formulated according to the addition of CHX diacetate (0 [control], 0.01, 0.05, 0.1 and 0.2%) in the two ER. For UTS and DC, specimens were constructed and tested after 24h. For WS, SO and CR, after specimens build-up, they were stored in water and the properties measured after 60 days. The occlusal enamel of fifty molars was removed and the adhesives were applied in dentine surface after 37% phosphoric acid etching. After composite resin build-ups, specimens were longitudinally sectioned to obtain resin-dentine bonded sticks (0.8mm(2)). Specimens were tested in tension at 0.5mm/min in the IM or 1Y. For NL, 2 bonded sticks from each tooth were prepared and analyzed under SEM. The data were submitted to appropriate statistical analysis (α=0.05).

Results: The addition of CHX did not influence UTS, DC, WS and SO (p<0.05). Higher CR was observed in adhesives with higher concentration of CHX (p<0.05). After 1Y, significant reductions of μTBS and increases of NL were observed in the control groups (p<0.05). Reductions of μTBS and increase of NL over time were not observed (AM) for CHX-containing adhesives or it was less pronounced than the control (XP) regardless of the CHX concentration.

Conclusions: The addition of CHX diacetate in concentrations until 0.2% in the simplified ER adhesive systems may be an alternative to increase the long-term stability of resin-dentine interfaces, without jeopardizing the adhesives' mechanical properties evaluated.

Keywords: Adhesives systems; Chlorhexidine; Durability; Long-term; Microtensile bond strength; Nanoleakege.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acid Etching, Dental / methods
Adolescent
Adult
Chlorhexidine / chemistry*
Composite Resins / chemistry
Dental Bonding
Dental Leakage / classification
Dental Materials / chemistry
Dentin / ultrastructure*
Dentin-Bonding Agents / chemistry*
Humans
Materials Testing
Methacrylates / chemistry
Microscopy, Electron, Scanning
Polymerization
Polyurethanes / chemistry
Solubility
Stress, Mechanical
Surface Properties
Surface-Active Agents / chemistry*
Tensile Strength
Time Factors
Water / chemistry
Young Adult

Substances

Composite Resins
Dental Materials
Dentin-Bonding Agents
Methacrylates
Polyurethanes
Surface-Active Agents
XP-Bond
Water
urethane dimethacrylate luting resin
methacryloyloxydecyl dihydrogen phosphate
Chlorhexidine