Evaluation of subfoveal choroidal thickness in children with type 1 diabetes mellitus: an EDI-OCT study

Semin Ophthalmol. 2014 Jan;29(1):27-31. doi: 10.3109/08820538.2013.838279. Epub 2013 Nov 19.

Abstract

Purpose: To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in children with type 1 diabetes without diabetic retinopathy.

Methods: In this prospective and comparative study, 41 diabetic children without diabetic retinopathy and 42 age-matched healthy subjects were enrolled. The SFCT was measured by EDI-OCT. Correlations between SFCT and diabetic parameters such as fasting glucose level, HbA1c, age, or duration of diabetes were also evaluated.

Results: The mean SFCT value was 375.3 ± 66.5 μm in the eyes with diabetes and 356.4 ± 52.0 μm in the control group. The SFCT was not correlated with fasting glucose level, HbA1c, age, or duration of diabetes.

Conclusion: This study showed that SFCT of diabetic children are similar to those of healthy controls. In addition, SFCT are not affected by fasting glucose level, HbA1c, age, or duration of diabetes.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Blood Glucose / metabolism
  • Child
  • Child, Preschool
  • Choroid / pathology*
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetic Retinopathy / complications
  • Female
  • Fovea Centralis
  • Glycated Hemoglobin / metabolism
  • Humans
  • Male
  • Prospective Studies
  • Tomography, Optical Coherence

Substances

  • Blood Glucose
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human