Resolution of "salt and pepper" appearance of the skull with vitamin D therapy

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S194-7. doi: 10.4103/2230-8210.119569.

Abstract

Chronic hypovitaminosis D leads to state of decreased mineralization and generalized osteomalacia. It also results in secondary hyperparathyroidism causing increased bone turn over and decreased bone mass, manifested radiologically as a "salt and pepper" appearance in skull, subperiosteal resorption, bone cysts and lytic lesions. In this case, a young male patient with hypovitaminosis D and secondary hyperparathyroidism, radiological features show resolution of "salt and pepper" appearance of the skull with vitamin D in 11 months and regression of other lytic lesions.

Keywords: Osteitis fibrosa cystica; salt and pepper appearance; secondary hyperparathyroidism; vitamin D deficiency.

Publication types

  • Case Reports