Abstract
A new oleanane-type triterpenoidal saponin, 3-O-β-D-glucopyranosyl-hederagenin 23-O-α-D-ribofuranoside (1), was isolated from the roots of Pulsatilla chinensis, and its structure was established on the basis of the spectral data. Compounds 2, 7 and 8 showed moderate cytotoxic activity by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazoliumbromide assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Line, Tumor
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Drug Screening Assays, Antitumor
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Humans
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Magnetic Resonance Spectroscopy
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Oleanolic Acid / analogs & derivatives*
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Oleanolic Acid / chemistry
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Oleanolic Acid / isolation & purification
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Oleanolic Acid / pharmacology
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Pulsatilla / chemistry*
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Saponins / chemistry
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Saponins / isolation & purification*
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Saponins / pharmacology
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Spectrometry, Mass, Electrospray Ionization
Substances
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Saponins
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oleanane
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Oleanolic Acid