The E23K polymorphism of the KCNJ11gene is associated with lower insulin release in patients with autosomal dominant polycystic kidney disease

Nefrologia. 2013 Nov 13;33(6):855-8. doi: 10.3265/Nefrologia.pre2013.May.12111.
No abstract available

MeSH terms

  • Adult
  • Alleles
  • Blood Glucose / analysis
  • Body Weight
  • Female
  • Genotype
  • Glucose Tolerance Test
  • Humans
  • Insulin / metabolism*
  • Insulin Resistance / genetics
  • Insulin Secretion
  • Islets of Langerhans / metabolism
  • Lipids / blood
  • Male
  • Polycystic Kidney, Autosomal Dominant / genetics*
  • Polycystic Kidney, Autosomal Dominant / physiopathology
  • Polymorphism, Single Nucleotide*
  • Potassium Channels, Inwardly Rectifying / genetics*

Substances

  • Blood Glucose
  • Insulin
  • Kir6.2 channel
  • Lipids
  • Potassium Channels, Inwardly Rectifying