Abstract
The one-pot and direct synthesis of 7,9-dialkylpurin-8-one analogues with broad substrate scope has been developed. This copper-catalyzed C-H oxidation reaction could avoid multistep synthesis of quaternary ammonium salts and expand the scope of halogenated alkanes. Moreover, benzimidazole derivatives are also applicable in the catalytic system.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkanes / chemistry
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Catalysis
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Copper / chemistry
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Iodides / chemistry
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Molecular Structure
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Oxidation-Reduction
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Purines / chemical synthesis*
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Purines / chemistry
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Quaternary Ammonium Compounds / chemistry
Substances
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Alkanes
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Iodides
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Purines
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Quaternary Ammonium Compounds
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Copper
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cuprous iodide