This paper deal with a manuscript from the years 1714-1720, originating most probably from the hospital of the Brothers of Mercy in Nové Mesto nad Metují. it contains the records of the hospital pharmacy about the drugs prepared for both patients and monks who operated this hospital. The included drugs were mainly intended for elderly males. The manuscript lists about fifteen hundred drugs and more than three hundred active ingredients, of which about two thirds were of plant origin. The paper presents the compositions of more important drugs and partly deals also with their preparation.