Abstract
Nonsteroidal anti-inflammatory drugs (NSAIDs) are nowadays widely used in ophthalmology to reduce eye inflammation, pain, and cystoid macular edema associated with cataract surgery. Recently, new topical NSAIDs have been approved for topical ophthalmic use, allowing for greater drug penetration into the vitreous. Hence, new therapeutic effects can be achieved, such as reduction of exudation secondary to age-related macular degeneration or diabetic maculopathy. We provide an updated review on the clinical use of NSAIDs for retinal diseases, with a focus on the potential future applications.
MeSH terms
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Administration, Topical*
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Aging
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Animals
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Anti-Inflammatory Agents, Non-Steroidal / administration & dosage*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
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Cataract Extraction
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Complement System Proteins / metabolism
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Diabetic Retinopathy / drug therapy
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Disease Progression
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Humans
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Macular Degeneration / drug therapy
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Macular Edema / drug therapy*
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Prostaglandin-Endoperoxide Synthases / metabolism
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Prostaglandins / metabolism
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Retinal Diseases / drug therapy
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Prostaglandins
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Complement System Proteins
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Prostaglandin-Endoperoxide Synthases