1.6 μm eye-safe emission of a diode pumped Er,Yb co-doped YAG ceramic laser is firstly demonstrated. Operation of the ceramic laser under different ceramic sample lengths, co-doping concentrations and control temperatures were experimentally investigated. A maximum output power of 222 mW was achieved at an absorbed pump power of 8.1 W, corresponding to a conversion efficiency of 2.74%. Laser emission at 1.05 μm for transition of the Yb(3+) ions was also studied on the same ceramic samples. The results clearly show the existence of resonantly energy transfer from the Yb(3+) ions to Er(3+) ions.