Gold nanoparticles/polyaniline Langmuir-Blodgett Film modified glassy carbon electrode as voltammetric sensor for detection of epinephrine and uric acid

Talanta. 2013 Dec 15:117:333-7. doi: 10.1016/j.talanta.2013.09.035. Epub 2013 Sep 25.

Abstract

Gold nanoparticles/polyaniline nanocomposite thin film was deposited onto the surface of glassy carbon electrode(GCE) by Langmuir-Blodgett(LB) technology to fabricate a new voltammetric sensor (GNPs/PAn-LB GCE) for epinephrine(EP) and uric acid(UA) detection. Cyclic voltammetry, electrochemical impedance spectroscopy and atomic force microscopy were employed to study the characteristic of the GNPs/PAn-LB film. Electrochemical behaviors of EP and UA at the modified electrode were investigated in pH 6.6 phosphate buffer solutions. A sensitive electroanalytical method for simultaneous determination of EP and UA was proposed with high precision and good reproducibility.

Keywords: Epinephrine; Gold nanoparticles; Langmuir–Blodgett Film; Polyaniline; Uric acid; Voltammetric sensor.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aniline Compounds / chemistry*
  • Ascorbic Acid / chemistry
  • Carbon
  • Electrochemical Techniques
  • Electrodes
  • Epinephrine / blood*
  • Gold / chemistry*
  • Humans
  • Metal Nanoparticles / chemistry*
  • Microscopy, Atomic Force
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Uric Acid / blood*

Substances

  • Aniline Compounds
  • polyaniline
  • Uric Acid
  • Carbon
  • Gold
  • Ascorbic Acid
  • Epinephrine