Same day tri-modality functional brain mapping prior to resection of a lesion involving eloquent cortex: technical feasibility

Neuroradiol J. 2013 Oct;26(5):548-54. doi: 10.1177/197140091302600508. Epub 2013 Nov 7.

Abstract

Non-invasive functional evaluation of the brain complements structural MRI imaging and has largely supplanted invasive techniques such as awake craniotomy. Techniques used for functional mapping of the brain include BOLD-functional MRI (fMRI), magnetoencephalography (MEG), and transcranial magnetic stimulation (TMS). We describe the case of a right-handed patient with a lesion centered in the left inferior perirolandic cortex who underwent fMRI, MEG, and TMS on a single day to facilitate maximal lesion resection while preserving eloquent cortex and eloquent white matter tracts.

Keywords: brain tumor; functional MRI; image-guided navigation; magnetoencephalography; multimodality; transcranial magnetic stimulation.

Publication types

  • Case Reports

MeSH terms

  • Brain / pathology
  • Brain / physiopathology*
  • Brain / surgery
  • Brain Mapping / methods*
  • Brain Neoplasms / pathology
  • Brain Neoplasms / physiopathology
  • Brain Neoplasms / surgery
  • Cerebral Cortex / pathology
  • Cerebral Cortex / physiopathology*
  • Cerebral Cortex / surgery
  • Female
  • Functional Neuroimaging / methods*
  • Glioma / pathology
  • Glioma / physiopathology*
  • Glioma / surgery
  • Humans
  • Magnetic Resonance Imaging / methods
  • Magnetoencephalography
  • Middle Aged
  • Neuronavigation / methods
  • Transcranial Magnetic Stimulation