Myths and mysteries surrounding bacillus Calmette-Guérin therapy for bladder cancer

Ashish M Kamat; Sima Porten

doi:10.1016/j.eururo.2013.10.016

Myths and mysteries surrounding bacillus Calmette-Guérin therapy for bladder cancer

Eur Urol. 2014 Feb;65(2):267-9. doi: 10.1016/j.eururo.2013.10.016. Epub 2013 Oct 26.

Authors

Ashish M Kamat¹, Sima Porten²

Affiliations

¹ Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA. Electronic address: akamat@mdanderson.org.
² Department of Urology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.

Abstract

Intravesical therapy with bacillus Calmette-Guérin has proven effects for reducing recurrence, progression, and death from non-muscle-invasive bladder cancer. These advantages are seen mainly when appropriate maintenance therapy is used for 1-3 years, in the context of appropriate patient selection, tumor management, and symptom support for potential side effects.

Publication types

Editorial

MeSH terms

Administration, Intravesical
Antineoplastic Agents / administration & dosage*
Antineoplastic Agents / adverse effects
BCG Vaccine / administration & dosage*
BCG Vaccine / adverse effects
Evidence-Based Medicine
Humans
Neoplasm Invasiveness
Neoplasm Recurrence, Local
Risk Assessment
Risk Factors
Treatment Outcome
Urinary Bladder Neoplasms / drug therapy*
Urinary Bladder Neoplasms / pathology

Substances

Antineoplastic Agents
BCG Vaccine

Grants and funding

P30 CA016672/CA/NCI NIH HHS/United States