Gene silencing in plants: a diversity of pathways

Biochim Biophys Acta. 2013 Dec;1829(12):1300-8. doi: 10.1016/j.bbagrm.2013.10.005. Epub 2013 Nov 1.

Abstract

Eukaryotic organisms have evolved a variety of gene silencing pathways in which small RNAs, 20- to 30-nucleotides in length, repress the expression of sequence homologous genes at the transcriptional or post-transcriptional levels. In plants, RNA silencing pathways play important roles in regulating development and response to both biotic and abiotic stresses. The molecular basis of these complex and interconnected pathways has emerged only in recent years with the identification of many of the genes necessary for the biogenesis and action of small RNAs. This review covers the diversity of RNA silencing pathways identified in plants.

Keywords: Genetic screen; PTGS; RNA silencing; Small RNAs; TGS.

Publication types

  • Review

MeSH terms

  • Gene Expression Regulation, Plant*
  • Gene Silencing*
  • Plant Proteins / antagonists & inhibitors*
  • Plant Proteins / genetics
  • Plants / genetics*
  • RNA Processing, Post-Transcriptional*
  • Signal Transduction*

Substances

  • Plant Proteins