Primary splenic tubercular abscess in an immunocompromised patient-rapid diagnosis by line probe assay

J Clin Diagn Res. 2013 Sep;7(9):1996-8. doi: 10.7860/JCDR/2013/6163.3382. Epub 2013 Aug 12.

Abstract

Diagnosing extra-pulmonary tuberculosis is a challenge that can confound even the most practiced clinicians as clinical manifestations are vague, non-specific and typical chest radiograph findings may not be evident till late in the disease. Conventional methods for mycobacteriological culture and drug susceptibility testing are slow and cumbersome. Novel technologies for rapid detection of Mycobacterium tuberculosis and its anti-TB drug resistance have therefore become a priority hence with the development of molecular line probe assays are most advanced. Herewith we are reporting a case of splenic tuberculosis in an immunocompromised patient for its rarity and to emphasis the fact that such patients can be diagnosed early for better treatment outcome to enhance the longevity if a health setup possesses all the modern diagnostic services.

Keywords: Extra–pulmonary tuberculosis; Immunocompromised; Line probe assay; Splenic tubercular abscess.