Complementary somatic mutations of KCNJ5, ATP1A1, and ATP2B3 in sporadic aldosterone producing adrenal adenomas

Endocr Relat Cancer. 2014 Jan 8;21(1):L1-4. doi: 10.1530/ERC-13-0466. Print 2014 Feb.

Authors

Ravi Kumar Dutta¹, Jenny Welander, Michael Brauckhoff, Martin Walz, Piero Alesina, Thomas Arnesen, Peter Söderkvist, Oliver Gimm

Affiliation

¹ Department of Clinical and Experimental Medicine, Faculty of Health Sciences Linköping University, SE-58183, Linköping Sweden Department of Surgery Haukeland University Hospital, Bergen Norway Department of Surgical Sciences Institute of Medicine, University of Bergen, Bergen Norway Klinik für Chirurgie and Zentrum für Minimal Invasive Chirurgie, Klinikum Essen-Mitte, Essen Germany Department of Molecular Biology Institute of Medicine, University of Bergen, Bergen Norway Department of Clinical Genetics County Council of Östergötland, Linköping Sweden Department of Surgery County Council of Östergötland, Linköping Sweden.

PMID: 24179102
DOI: 10.1530/ERC-13-0466

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adrenal Cortex Neoplasms / genetics*
Adrenal Cortex Neoplasms / metabolism
Adrenocortical Adenoma / genetics*
Adrenocortical Adenoma / metabolism*
Adult
Aged
Aldosterone / metabolism
Base Sequence
Female
G Protein-Coupled Inwardly-Rectifying Potassium Channels / genetics*
Humans
Hyperaldosteronism / genetics*
Male
Middle Aged
Molecular Sequence Data
Mutation
Plasma Membrane Calcium-Transporting ATPases / genetics*
Sequence Analysis, DNA
Sodium-Potassium-Exchanging ATPase / genetics*

Substances

G Protein-Coupled Inwardly-Rectifying Potassium Channels
KCNJ5 protein, human
Aldosterone
ATP1A1 protein, human
Plasma Membrane Calcium-Transporting ATPases
ATP2B3 protein, human
Sodium-Potassium-Exchanging ATPase