Abstract
The effect of ligand structure on the cytotoxicity of cationic CdSe/ZnS quantum dots (QDs) was systematically investigated using mono- and bidentate ligands. Monothiol-functionalized QDs are more cytotoxic than dithiol-functionalized QDs.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Cations / chemistry*
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Cations / pharmacology
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Cell Death / drug effects
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Coordination Complexes / chemistry
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Coordination Complexes / pharmacology*
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Cytotoxins / chemistry*
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Cytotoxins / pharmacology
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Drug Evaluation, Preclinical
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HeLa Cells
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Humans
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Ligands
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Nanoparticles / chemistry
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Necrosis
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Quantum Dots / chemistry*
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Structure-Activity Relationship
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Sulfhydryl Compounds / chemistry
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Sulfhydryl Compounds / pharmacology*
Substances
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Cations
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Coordination Complexes
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Cytotoxins
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Ligands
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Sulfhydryl Compounds