Portal vein arterialization as a bridge procedure against acute liver failure after extended hepatectomy for hilar cholangiocarcinoma

Surg Innov. 2014 Aug;21(4):372-5. doi: 10.1177/1553350613507146. Epub 2013 Oct 30.

Abstract

Background: Acute liver failure (ALF) is a severe and highly fatal complication arising after extended hepatobiliary surgery. The aim of this study was to investigate the primary management experience of portal vein arterialization (PVA) as a bridge procedure to reduce the risk of ALF for hilar cholangiocarcinoma (HCCA) after extended hepatectomy.

Method: Between January 2010 and January 2012, 4 patients with HCCA with possible involvement of the right and/or left hepatic artery underwent resectional surgery with reconstruction of the right or left artery blood flow by arterializations of portal vein.

Results: The arteries used for this surgical procedure included gastroduodenal artery (n = 2), common hepatic artery (n = 1), and right gastroepiploic artery (n = 1). PVA was verified as a key point during the course of the disorder between surgery and postoperative recovery. During follow-up, 1 patient suffered secondary portal hypertension and was subsequently cured by interventional artery coil embolization.

Conclusion: PVA can be indicated where there is arterial involvement in HCCA patients who have undergone extended hepatectomy or trisectionectomy.

Keywords: acute liver failure; extended hepatectomy; hilar cholangiocarcinoma; portal vein arterialization.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anastomosis, Surgical / methods
  • Angiography / methods
  • Arteriovenous Shunt, Surgical / methods*
  • Bile Duct Neoplasms / pathology
  • Bile Duct Neoplasms / surgery*
  • Bile Ducts, Intrahepatic*
  • China
  • Cholangiocarcinoma / pathology
  • Cholangiocarcinoma / surgery*
  • Female
  • Hepatectomy / adverse effects*
  • Hepatectomy / methods
  • Hepatic Artery / surgery
  • Humans
  • Liver Circulation / physiology
  • Liver Failure, Acute / etiology
  • Liver Failure, Acute / prevention & control*
  • Magnetic Resonance Imaging / methods
  • Male
  • Microsurgery
  • Middle Aged
  • Patient Safety
  • Portal Vein / surgery
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / surgery
  • Retrospective Studies
  • Risk Assessment
  • Sampling Studies
  • Tomography, X-Ray Computed / methods
  • Treatment Outcome