Successful treatment of post-neurosurgical multidrug-resistant Pseudomonas aeruginosa meningo-encephalitis with combination therapy of colistin, rifampicin and doripenem

J Antimicrob Chemother. 2014 Mar;69(3):857-9. doi: 10.1093/jac/dkt437. Epub 2013 Oct 29.

Authors

Paola Morelli¹, Antonella Ferrario, Federica Tordato, Aurora Piazza, Erminia Casari

Affiliation

¹ Infectious Diseases Unit, Hospital Health Direction, IRCCS Istituto Clinico Humanitas, via Manzoni 56, 20089 Rozzano, Milano, Italy.

PMID: 24169582
DOI: 10.1093/jac/dkt437

No abstract available

Keywords: CSF; carbapenem; infection.

Publication types

Case Reports
Letter

MeSH terms

Adult
Anti-Bacterial Agents / therapeutic use*
Carbapenems / therapeutic use*
Colistin / therapeutic use*
Doripenem
Drug Resistance, Multiple, Bacterial*
Drug Therapy, Combination / methods
Humans
Male
Meningoencephalitis / drug therapy*
Meningoencephalitis / microbiology
Microbial Sensitivity Tests
Pseudomonas Infections / drug therapy*
Pseudomonas Infections / microbiology
Pseudomonas aeruginosa / drug effects
Pseudomonas aeruginosa / isolation & purification
Rifampin / therapeutic use*
Surgical Wound Infection / drug therapy
Surgical Wound Infection / microbiology
Treatment Outcome

Substances

Anti-Bacterial Agents
Carbapenems
Doripenem
Rifampin
Colistin