HLA-G polymorphism and breast cancer

Int J Immunogenet. 2014 Apr;41(2):143-8. doi: 10.1111/iji.12092. Epub 2013 Oct 25.

Abstract

The aim of this study was to explore a possible influence of the HLA-G coding polymorphisms on the susceptibility to breast cancer development in Brazilian subjects; however, none of the HLA-G variation sites evaluated was influencing breast cancer susceptibility indicating that the variation in the HLA-G coding region is not a risk factor for breast cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alleles
  • Brazil
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / immunology
  • Case-Control Studies
  • Female
  • Genetic Predisposition to Disease
  • Genotype
  • HLA-G Antigens / genetics*
  • Humans
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Risk Factors

Substances

  • HLA-G Antigens