[The interaction between nerve cells and carbon nanotube networks made by CVD process investigation]

Biofizika. 2013 May-Jun;58(3):524-30.
[Article in Russian]

Abstract

In this research we investigate neuroblastoma cells cultivated on single-walled carbon nanotubes networks made by CVD method on silicon substrates. The complex analysis of grown cells made by atomic force, electron microscopy and Raman spectroscopy was carried out and the effect of nanotube growth process on proliferation factor was investigated. It is shown that despite of a weak decrease in proliferation, cell morphology remains unchanged and no physical or chemical interaction between carbon nanotubes and cells is observed. The results of the research can be used to investigate the interaction between conductive nanomaterials and cells for the development of neural replacement implants. Also they can be useful in bio-electronic interface investigation of signal propagation in neurons.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cell Proliferation*
  • Humans
  • Microscopy, Atomic Force
  • Microscopy, Electron, Scanning
  • Nanotubes, Carbon / chemistry*
  • Neuroblastoma / metabolism*
  • Neuroblastoma / ultrastructure
  • Neurons / metabolism*
  • Neurons / ultrastructure
  • Spectrum Analysis, Raman

Substances

  • Nanotubes, Carbon