Characterization of CRF56_cpx, a new circulating B/CRF02/G recombinant form identified in MSM in France

AIDS. 2013 Sep 10;27(14):2309-12. doi: 10.1097/QAD.0b013e3283632e0c.

Abstract

Several B/CRF02_AG Unique Recombinant Forms (URFs) have previously been identified in France. Here we show that one of them (URF5_B/02/G) is emerging in MSM, a high-risk population where HIV incidence and number of superinfections are increasing. We describe this new Circulating Recombinant Form, CRF56_cpx, estimate the time to its most recent common ancestor, investigate its origins and show that it probably shares common ancestors with strains from the East Mediterranean.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cluster Analysis
  • Evolution, Molecular
  • France / epidemiology
  • HIV Infections / epidemiology*
  • HIV Infections / virology*
  • HIV-1 / classification*
  • HIV-1 / genetics*
  • HIV-1 / isolation & purification
  • Humans
  • Incidence
  • Molecular Epidemiology
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Viral / genetics
  • Recombination, Genetic*
  • Sequence Analysis, DNA
  • Young Adult

Substances

  • RNA, Viral

Associated data

  • GENBANK/KC852172
  • GENBANK/KC852173
  • GENBANK/KC852174