Experience with real time continuous glucose monitoring in stabilising fluctuating glycaemia during intensive care of the preterm infant of a diabetic mother

J Matern Fetal Neonatal Med. 2014 Sep;27(13):1389-91. doi: 10.3109/14767058.2013.858686. Epub 2013 Nov 13.

Abstract

Objective: The newborns of diabetic mothers suffer from perinatal complications more frequently than the newborns of healthy women.

Methods: We used for 7 days a real time continuous glucose monitoring system (RT-CGMS) to monitor glucose homeostasis and manage glucose administration in a premature newborn of a diabetic mother.

Results: The boy was born at 35 + 5 gestational weeks with typical signs of diabetic fetopathy. RT-CGMS revealed 2 late hypoglycaemia episodes on the 2nd and 4th days. The sensor readings correlated well with glycaemia measured in the laboratory (r = 0.908, p = 0.005). To support conclusions of this case report, we attached the data of five other preterm newborns of diabetic mothers who were later successfully treated according to the RT-CGMS data as well.

Conclusions: This approach allows timely response to glycaemia instability and is applicable even in preterm infants.

Keywords: Diabetes mellitus; fetopathy; glucose administration; glycaemia measurement; hypoglycaemia; newborn of a diabetic mother.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Glucose*
  • Diabetes Mellitus, Type 1
  • Female
  • Humans
  • Infant, Premature / blood*
  • Intensive Care, Neonatal / methods*
  • Male
  • Monitoring, Physiologic
  • Pregnancy
  • Pregnancy in Diabetics

Substances

  • Blood Glucose