Synthesis and structural characterization of fluorinated thiosemicarbazones

Juan L Bautista; Marcos Flores-Alamo; Jorge Tiburcio; Rebeca Vieto; Hugo Torrens

doi:10.3390/molecules181013111

Synthesis and structural characterization of fluorinated thiosemicarbazones

Molecules. 2013 Oct 22;18(10):13111-23. doi: 10.3390/molecules181013111.

Authors

Juan L Bautista¹, Marcos Flores-Alamo, Jorge Tiburcio, Rebeca Vieto, Hugo Torrens

Affiliation

¹ Facultad de Ciencias Químicas, Universidad Autónoma Benito Juárez de Oaxaca. Av. Universidad S/N Cinco Señores, Oaxaca de Juárez, Oaxaca 68000, Mexico. torrens@unam.mx.

Abstract

Six new fluorinated thiosemicarbazones R‑C(R')=N-NH-C(S)NH(2) (R = 2,4-C(6)H(3)F(2), R' = H (1); R = 2,5-C(6)H(3)F(2), R' = H (2); R = 2,6-C(6)H(3)F(2), R' = H (3); R = 3,4-C(6)H(3)F(2), R' = H (4); R = 3,5-C(6)H(3)F(2), R' = H (5) and R = 4-C(6)H(4)F, R' = C(6)H(5), (6)) have been prepared. The molecular structures of compounds 1 to 6 have been determined.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Benzaldehydes / chemical synthesis
Benzaldehydes / chemistry
Crystallography, X-Ray
Halogenation
Hydrocarbons, Fluorinated / chemical synthesis*
Hydrocarbons, Fluorinated / chemistry
Hydrogen Bonding
Models, Molecular
Molecular Conformation
Thiosemicarbazones / chemical synthesis*
Thiosemicarbazones / chemistry

Substances

Benzaldehydes
Hydrocarbons, Fluorinated
Thiosemicarbazones