Three new ursane-type triterpenoids from the aerial parts of Isodon excisoides

J Asian Nat Prod Res. 2013 Sep;15(9):962-8. doi: 10.1080/10286020.2013.837458. Epub 2013 Oct 24.

Abstract

Three new ursane-type triterpenoids, 2α,3β-dihydroxy-11α,12α-epoxy-urs-28,13β-olide (1), 2α,3β,24-trihydroxy-11α,12α-epoxy-urs-28,13β-olide (2), and 2α,3α,24-trihydroxy-11,20(30)-dien-urs-28,13β-olide (6), together with six known ursane-type triterpenoids (3-5, 7-9), were isolated from the EtOAc extract of the aerial parts of Isodon excisoides. Their structures were elucidated on the basis of 1D NMR and 2D NMR analyses as well as HRMS experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Isodon / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • 2alpha,3alpha,24-trihydroxy-11,20(30)-dien-urs-28,13beta-olide
  • 2alpha,3beta,24-trihydroxy-11alpha,12alpha-epoxy-urs-28,13beta-olide
  • 2alpha,3beta-dihydroxy-11alpha,12alpha-epoxy-urs-28,13beta-olide
  • Drugs, Chinese Herbal
  • Triterpenes