[Off-label indications for topical tacrolimus]

Hautarzt. 2013 Oct;64(10):752-6. doi: 10.1007/s00105-013-2594-1.
[Article in German]

Abstract

The topical calcineurin antagonist tacrolimus plays an important role in the treatment of different forms of eczema because of its favorable risk profile. In addition, different off-label indications have been clinically tested where tacrolimus ointment has achieved clinical improvement. This article discusses off-label treatment of vitiligo, seborrheic dermatitis, steroid rosacea, perioral dermatitis, rosacea and lichen sclerosus.

Publication types

  • English Abstract

MeSH terms

  • Administration, Topical
  • Chronic Disease
  • Dermatologic Agents / administration & dosage
  • Dermatologic Agents / adverse effects
  • Drug-Related Side Effects and Adverse Reactions / etiology*
  • Drug-Related Side Effects and Adverse Reactions / prevention & control
  • Evidence-Based Medicine*
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Immunosuppressive Agents / adverse effects
  • Off-Label Use*
  • Skin Diseases / drug therapy*
  • Tacrolimus / administration & dosage*
  • Tacrolimus / adverse effects*
  • Treatment Outcome

Substances

  • Dermatologic Agents
  • Immunosuppressive Agents
  • Tacrolimus