A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state

Lab Chip. 2014 Jan 7;14(1):161-6. doi: 10.1039/c3lc50923k.

Abstract

This communication presents quantitative studies of the dynamic adhesion behavior of mesenchymal stem cells (MSCs) enabled by the combination of cell-surface receptor-ligand interactions and three-dimensional hydrodynamic control by microtopography.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adipocytes / cytology
  • Cell Adhesion
  • Cell Differentiation
  • Cells, Cultured
  • Flow Cytometry / instrumentation
  • Flow Cytometry / methods*
  • HL-60 Cells
  • Humans
  • Ligands
  • Mesenchymal Stem Cells / cytology*
  • Mesenchymal Stem Cells / metabolism
  • Osteoblasts / cytology
  • Phenotype
  • Receptors, Cell Surface / chemistry
  • Receptors, Cell Surface / metabolism

Substances

  • Ligands
  • Receptors, Cell Surface