Prevalence and management of coronary chronic total occlusions in a tertiary Veterans Affairs hospital

Catheter Cardiovasc Interv. 2014 Oct 1;84(4):637-43. doi: 10.1002/ccd.25264. Epub 2013 Nov 13.

Abstract

Objectives: We sought to determine the contemporary prevalence and management of coronary chronic total occlusions (CTO) in a veteran population.

Background: The prevalence and management of CTOs in various populations has received limited study.

Methods: We collected clinical and angiographic data in consecutive patients that underwent coronary angiography at our institution between January 2011 and December 2012. Coronary artery disease (CAD) was defined as ≥50% diameter stenosis in ≥1 coronary artery. CTO was defined as total coronary artery occlusion of ≥3 month duration.

Results: Among 1,699 patients who underwent angiography during the study period, 20% did not have CAD, 20% had CAD and prior coronary artery bypass graft surgery (CABG), and 60% had CAD but no prior CABG. The prevalence of CTO among CAD patients with and without prior CABG was 89 and 31%, respectively. Compared to patients without CTO, CTO patients had more co-morbidities, more extensive CAD and were more frequently referred for CABG. Percutaneous coronary intervention (PCI) to any vessel was performed with similar frequency in patients with and without CTO (50% vs. 53%). CTO PCI was performed in 30% of patients without and 15% of patients with prior CABG with high technical (82 and 75%, respectively) and procedural success rates (80 and 73%, respectively).

Conclusions: In a contemporary veteran population, coronary CTOs are highly prevalent and are associated with more extensive co-morbidities and higher likelihood for CABG referral. PCI was equally likely to be performed in patients with and without CTO.

Keywords: coronary artery disease; coronary occlusion; percutaneous coronary intervention.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Chronic Disease
  • Comorbidity
  • Coronary Angiography
  • Coronary Artery Bypass*
  • Coronary Occlusion / diagnosis
  • Coronary Occlusion / epidemiology*
  • Coronary Occlusion / therapy*
  • Female
  • Hospitals, Veterans*
  • Humans
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention*
  • Predictive Value of Tests
  • Prevalence
  • Referral and Consultation
  • Retrospective Studies
  • Risk Factors
  • Severity of Illness Index
  • Tertiary Care Centers*
  • Time Factors
  • Treatment Outcome
  • United States / epidemiology
  • United States Department of Veterans Affairs*