First report of the toxin profile of Dinophysis sacculus Stein from LC-MS analysis of laboratory cultures

Toxicon. 2013 Dec 15:76:221-4. doi: 10.1016/j.toxicon.2013.10.012. Epub 2013 Oct 16.

Abstract

Dinophysis sacculus is associated with DSP outbreaks especially in the Mediterranean Sea and is supposed to be mildly toxic based on few toxin results from field samples. First report of LC-MS analysis of D. sacculus cultures from Galicia (NW Spain) showed moderate amounts of OA (7.8 pg cell(-1)) comparable to those found in Dinophysis acuminata from the same region, PTX2 (13.2 pg cell(-1)) and trace amounts of DTX1 (0.8 pg OA equiv. cell(-1)). The contribution of D. sacculus to DSP outbreaks in the Galician Northern Rías should not be underestimated.

Keywords: DSP; Dinophysis sacculus; Galician Rías; Okadaic acid; Pectenotoxin-2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromatography, Liquid
  • Dinoflagellida / chemistry*
  • Dinoflagellida / metabolism
  • Environmental Monitoring
  • Humans
  • Marine Toxins / chemistry*
  • Marine Toxins / isolation & purification
  • Marine Toxins / metabolism
  • Mass Spectrometry
  • Okadaic Acid / chemistry
  • Okadaic Acid / isolation & purification
  • Okadaic Acid / metabolism
  • Pyrans / chemistry
  • Pyrans / isolation & purification
  • Pyrans / metabolism
  • Shellfish Poisoning / etiology
  • Spain

Substances

  • Marine Toxins
  • Pyrans
  • Okadaic Acid
  • dinophysistoxin 1