Incidence and outcomes of bepridil-induced interstitial pneumonia

Abstract

Background: The incidence of bepridil-induced pulmonary toxicity, such as interstitial pneumonia, is still unknown. The aim of the present study was to evaluate the incidence of bepridil-induced pulmonary toxicity.

Methods and results: A total of 253 patients treated with bepridil between January 2009 and January 2011 were retrospectively evaluated. Eight out of the 222 evaluable patients (male/female: 5/3, age range: 64-97 years, average age: 80.5 years, median age: 81.0 years) showed bepridil-induced pulmonary toxicity.

Conclusions: The incidence of bepridil-induced pulmonary toxicity was 3.60% in our study population.

Keywords: Bepridil; Drug-induced interstitial pneumonia; Pulmonary toxicity.